Journal of Ophthalmology

Research Article

Safety and Efficacy of Epithelium-On Corneal Collagen Cross-Linking Using a Multifactorial Approach to Achieve Proper Stromal Riboflavin Saturation

Table 2

Topographic changes during 1-year followup.
ParameterPreoperative ( 𝑛 = 6 1 )12 m postoperatively ( 𝑛 = 6 1 )
Precisio
 PE (μm) 7 1 . 5 6 ± 3 1 . 3 1 6 6 . 4 8 ± 2 8 . 8 1 ( 𝑃 = 0 . 0 1 )
 IRI (μm) 4 5 . 4 5 ± 2 2 . 6 0 4 2 . 1 8 ± 2 2 . 5 4 ( 𝑃 = 0 . 0 1 )
 Asym (D) 9 . 0 5 ± 5 . 5 0 8 . 1 2 ± 5 . 5 8 ( 𝑃 = 0 . 0 1 )
OPD
 Mean 𝐾 (D) 4 6 . 9 7 ± 5 . 2 1 4 6 . 7 7 ± 5 . 3 1 ( 𝑃 = 0 . 0 6 )
 Max 𝐾 (D) 5 5 . 5 5 ± 6 . 0 1 5 4 . 9 8 ± 5 . 7 8 ( 𝑃 = 0 . 0 2 )
 DSI 1 0 . 5 4 ± 5 . 3 0 9 . 7 1 ± 5 . 0 1 ( 𝑃 = 0 . 0 0 )
  𝑆 3, 5, 7 1 . 4 0 ± 0 . 8 0 1 . 3 2 ± 0 . 8 0 ( 𝑃 = 0 . 0 4 )
  𝑆 4, 6, 8 0 . 3 3 ± 0 . 2 1 0 . 3 4 ± 0 . 3 3 ( 𝑃 = 0 . 8 1 )
 Total HOA 4 . 8 0 ± 2 . 9 3 4 . 5 4 ± 2 . 7 2 ( 𝑃 = 0 . 0 5 )
PE: posterior elevation; IRI: irregularity index; Asym: asymmetry within 5 mm zone; DSI: differential sector index; HOA: higher order aberration.