786870.fig.002a
(a)
786870.fig.002b
(b)
Figure 2: (a) A binding domain of VEGFR1 and VEGFR2 are fused to create 2 dual-domain arms for each VEGF Trap-Eye molecule. (b) The Fc portion of the IgG is fused to the two dual-domain arms to create the VEGF Trap-Eye molecule (see [9]).