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Journal of Ophthalmology
Volume 2013 (2013), Article ID 908017, 6 pages
http://dx.doi.org/10.1155/2013/908017
Clinical Study

Flash Electroretinography and Pattern Visual Evoked Potential Changes in Ocular Hypertension Patients

1Kemalpaşa State Hospital, Clinic of Ophthalmology, 35730 Izmir, Turkey
2Beyoğlu Eye Training and Research Hospital, 34421 Istanbul, Turkey
3Salihli State Hospital, Clinic of Ophthalmology, 45310 Manisa, Turkey

Received 10 February 2013; Accepted 12 April 2013

Academic Editor: Huseyin Gursoy

Copyright © 2013 Ercüment Çavdar et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose. To evaluate the changes of flash electroretinography (fERG) and pattern visual evoked potentials (pVEP) in ocular hypertension (OHT) patients. Methods. Twenty-five OHT patients and 30 healthy volunteers were enrolled for this cross-sectional study. Opthalmologic examinations, visual field tests, pVEP and fERG were performed. The main outcome measures were the differences between pVEP and fERG parameters. Results. The mean age of OHT patients and volunteers were 57 ± 12.25 years (range 30–65 years), and 53.25 ± 12.0 years (range 30–65 years), respectively. The mean amplitude of the pVEP was statistically lower in the OHT group (P < 0.05). Latency of the two groups was different; however, the difference was not statistically significant (P > 0.05). In fERG of OHT group, there was a significant decrease in the amplitude of the oscillatory potentials (Ops), and a significant delay in latency of rod and cone waves (all P < 0.05). There was no significant change in the flicker fERG waves between the two groups (P > 0.05). Conclusions. Although we found a decrease in Ops amplitude and a prolonged latency in flicker fERG, only the decrease in Ops amplitude was statistically significant between the two groups. The amplitude of Ops wave and amplitude of pVEP may reflect early glaucomatous damage in OHT patients.