Vascular Adhesion Protein 1 in the Eye

Table 1

The function of vascular adhesion protein-1 in ocular diseases.

Eye diseases	Possible role of VAP-1	Reference
Uveitis	VAP-1 is involved in leukocyte infiltration into ocular tissues.	[11]
NVC	During acute inflammation, VAP-1 regulates both firm adhesion and transmigration; VAP-1 contributes to the recruitment of macrophages to CNV lesions and has a novel link with angiogenesis.	[12, 50]
DR	In chronic low-grade inflammation, VAP-1 may only regulate transmigration; sVAP-1 is increased and correlated with oxidative stress in the vitreous fluid.	[10, 64]
Tumor	VAP-1 is correlated with the angiogenesis and tumor growth.	[71, 72]

VAP-1: vascular adhesion protein-1.