Research Article

A New Combination Formula for Treatment of Fungal Keratitis: An Experimental Study

Table 5

Histopathological results of rabbits’ corneas after being sacrificed.

Antifungal formulaeFirst subgroupSecond subgroup
Left eyeRight eye (ketoconazole)Left eyeRight eye (placebo)

Rapid release PF 44Stromal macrophages
PMN (+)
Stromal macrophages
PMN (++)
Candida albicans
Stromal macrophages
PMN (+)
Stromal macrophages PMN (+++)
Candida albicans

Slow release PF 51Stromal macrophages
PMN (+)
Stromal macrophages
PMN (++)
Candida albicans
Stromal macrophagesStromal macrophages
PMN (+++)
Candida albicans

PMN: polymorph nuclear leucocytes; PF: polymer formula.