Sarcoidosis: Sex-Dependent Variations in Presentation and Management

Table 1

Pregnancy classes of medications used to treat systemic sarcoidosis.

Category	Systemic medication	Pregnancy class
Corticosteroid	Prednisone	C	Risk cannot be ruled out
	Methylprednisolone	C	Risk cannot be ruled out
Antimetabolite	Methotrexate	X	Should not be used during pregnancy
	Mycophenolate	D	Positive evidence of risk
	Azathioprine	D	Positive evidence of risk
Calcineurin inhibitor	Cyclosporine	C	Risk cannot be ruled out
Monoclonal antibody	Infliximab	B	No evidence of risk in humans
	Adalimumab	B	No evidence of risk in humans
	Etanercept	B	No evidence of risk in humans
Alkylating agents	Chlorambucil	D	Positive evidence of risk
	Cyclophosphamide	D	Positive evidence of risk