Effects of Misalignments in the Retinal Nerve Fiber Layer Thickness Measurements with Spectral Domain Optical Coherence Tomography
Table 4
Comparison of mean ± standard deviation (95% confidence interval) SD-OCT parameters between eyes with and without misalignments in the inferior area (sectors 3 and 4).
SD-OCT
AE ()
MAE ()
value†
AT (µm)
91.1 ± 14.6 (CI 62.5–119.7)
91.2 ± 15.3 (CI 61.2–121.1)
0.859
Quadrant, (µm)
Superior
112.5 ± 23.6 (CI 66.2–158.8)
112.9 ± 25.8 (CI 62.3–163.4)
0.830
Nasal
72.0 ± 12.7 (CI 47.1–96.9)
72.3 ± 13.5 (CI 45.8–98.7)
0.746
Inferior
114.8 ± 26.5 (CI 64.8–164.8)
114.3 ± 27.5 (CI 60.4–168.2)
0.838
Temporal
65.1 ± 10.7 (CI 44.1–86.1)
65.3 ± 13.1 (CI 39.6–90.9)
0.867
Clock-hour, (µm)
1
102.0 ± 25.3 (CI 52.4–151.6)
104.1 ± 30.9 (CI 43.5–164.6)
0.455
2
84.0 ± 17.6 (CI 49.5–118.5)
84.7 ± 18.8 (CI 47.9–121.5)
0.689
3
62.6 ± 12.5 (CI 38.1–87.1)
62.2 ± 11.8 (CI 39.1–85.3)
0.682
4
69.1 ± 13.7 (CI 42.2–96.0)
69.8 ± 15.8 (CI 38.8–100.7)
0.616
5
96.3 ± 24.3 (CI 48.7–143.9)
100.5 ± 32.2 (CI 37.2–163.8)
0.201
6
126.1 ± 32.5 (CI 62.4–189.8)
124.1 ± 34.7 (CI 56.1–192.1)
0.529
7
122.3 ± 31.4 (CI 60.8–183.8)
118.3 ± 28.9 (CI 61.7–174.9)
0.111
8
66.1 ± 15.3 (CI 36.1–96.1)
67.5 ± 21.1 (CI 26.1–108.8)
0.492
9
55.9 ± 18.2 (CI 20.2–91.6)
55.6 ± 18.0 (CI 20.3–90.8)
0.819
10
73.3 ± 10.3 (CI 53.1–93.5)
72.7 ± 9.8 (CI 53.5–91.9)
0.450
11
116.8 ± 29.2 (CI 59.6–174.0)
113.8 ± 27.7 (CI 59.5–168.0)
0.100
12
118.6 ± 35.2 (CI 49.6–187.6)
120.9 ± 36.6 (CI 49.2–192.6)
0.514
Signal strength
8.0 ± 0.7 (CI 6.6–9.4)
8.1 ± 0.8 (CI 6.5–9.6)
0.646
SD-OCT = spectral domain optical coherence tomography; AE = aligned exam; MAE = misaligned exam; AT = average thickness; CI = confidence interval. †Student’s -test.
