The Relationship between Visual Field Global Indices and Retinal Nerve Fiber Layer Thickness in Healthy Myopes

Table 4

The association between mean defect (MD) and RNFL thickness.

Per 10 μm increase in RNFL thickness				MD change (dB)	95% CIs			value
General linear model	OD	Model I	57	0.53	(0.14, 0.92)	0.34	0.11	0.011
		Model II		0.59	(0.18, 1.01)		0.22	0.007
	OS	Model I	57	0.74	(0.29, 1.19)	0.39	0.15	0.003
		Model II		0.79	(0.31, 1.26)		0.25	0.002
Mixed model^*		Model I	114	0.37	(0.07, 0.67)			0.018
		Model II		0.42	(0.11, 0.74)			0.010
		Model III		0.40	(0.08, 0.72)			0.016

The associations were expressed by the change of MD (dB) per 10 m (approximately 1 SD) increase of RNFL thickness.
Model I: unadjusted model.
Model II: adjusted for age, sex, refraction (diopters), and area of optic disc (mm²).
Model III: adjusted for age, sex, and ocular magnification scale based on Bennett’s formula.
^*The mixed model combined the data of both right eyes and left eyes accounting for intraindividual binocular correlation.
SD: standard deviation; RNFL: retinal nerve fiber layer; CI: confidence interval; OD: oculus dexter (the right eye); OS: oculus sinister (the left eye).