Obstructive Sleep Apnea Patients Having Surgery Are Less Associated with Glaucoma
Table 2
Incidence rates of glaucoma and multiple Cox regression model measured hazard rates ratio between two study cohorts.
Variable
Comparison cohort
OSA cohort
Crude HR (95% CI)
Adjusted HR (95% CI)
Event
PYs
Rate
Event
PYs
Rate
Total
191
44535
42.89
101
11109
90.91
2.12 (1.67–2.70)
1.88 (1.46–2.42)
Age group
0–44
42
22434
18.72
29
5576
52.01
2.77 (1.73–4.45)
2.42 (1.48–3.96)
45–54
54
11980
45.08
26
3019
86.12
1.90 (1.19–3.03)
1.64 (1.00–2.68)
≧55
95
10121
93.86
46
2514
182.95
1.95 (1.37–2.78)
1.65 (1.14–2.40)
Sex
Female
44
9350
47.06
30
2309
129.94
2.75 (1.73–4.38)
2.23 (1.37–3.65)
Male
147
35185
41.78
71
8801
80.68
1.93 (1.45–2.56)
1.75 (1.30–2.35)
Comorbidity
Without any comorbidity*
84
32703
25.69
30
5671
52.9
2.06 (1.36–3.13)
2.40 (1.58–3.66)
Hypertension
No
106
36464
29.07
51
7235
70.49
2.43 (1.74–3.39)
2.48 (1.76–3.50)
Yes
85
8071
105.31
50
3875
129.05
1.22 (0.86–1.73)
1.37 (0.96–1.97)
Diabetes
No
157
41504
37.83
84
10022
83.82
2.22 (1.70–2.89)
1.99 (1.50–2.62)
Yes
34
3031
112.17
17
1087
156.32
1.34 (0.75–2.41)
1.29 (0.70–2.38)
CAD
No
159
41148
38.64
68
8962
75.87
1.96 (1.48–2.61)
1.96 (1.46–2.62)
Yes
32
3387
94.47
33
2147
153.7
1.60 (0.98–2.60)
1.66 (1.01–2.72)
Hyperlipidemia
No
140
38724
36.15
60
7944
75.53
2.09 (1.54–2.83)
1.95 (1.42–2.66)
Yes
51
5811
87.77
41
3166
129.51
1.46 (0.97–2.21)
1.60 (1.05–2.43)
Model adjusted for age, sex, hypertension, diabetes, CAD, and hyperlipidemia.
*Model adjusted for age and sex. PYs: person-years; rate: incidence rate, per 10,000 person-years.