Clinical Study
Comparison of Latanoprost/Timolol with Carbonic Anhydrase Inhibitor and Dorzolamide/Timolol with Prostaglandin Analog in the Treatment of Glaucoma
Table 1
Patient background.
(a) |
| | Group 1 | Group 2 | |
| Cases | 55 cases | 57 cases | — |
| Ratio of male and female | 31 : 24 | 26 : 31 | 0.2648 |
| Age | years old | years old | 0.7161 | 32~85 years old | 27~85 years old |
| Disease type | | | | Primary open-angle glaucoma | 40 cases | 44 cases | 0.8194 | Normal tension glaucoma | 12 cases | 11 cases | Ocular hypertension | 3 cases | 2 cases |
| IOP before the change | mmHg | mmHg | 0.367 | 10~24 mmHg | 10~23 mmHg |
| MD value before the change | dB | dB | 0.8772 | −33.15~−0.13 dB | −21.73~−0.09 dB |
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(b) |
| | Used eye drops | Group 1 | Group 2 | | | 55 cases | 57 cases | — |
| Before the change | PG analogs | | | | Latanoprost | 52 | 44 | 0.0139 | Travoprost | — | 7 | Tafluprost | 3 | 3 | Bimatoprost | — | 3 | β-blocker | | | | Timolol | 51 | 39 | 0.0016 | Carteolol | 4 | 18 | CAI | | | | Dorzolamide | 13 | 38 | <0.0001 | Brinzolamide | 42 | 19 |
| After the change | PG analogs | | | | Latanoprost | — | 44 | — | Travoprost | — | 7 | Tafluprost | — | 3 | Bimatoprost | — | 3 | β-blocker | | | | Timolol | — | — | — | Carteolol | — | — | CAI | | | | Dorzolamide | 13 | — | — | Brinzolamide | 42 | — | Fixed-combination eye drops | | | | Latanoprost/timolol | 55 | — | — | Dorzolamide/timolol | — | 57 | — |
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