Inhibition of Corneal Neovascularization by Subconjunctival Injection of Fc-Endostatin, a Novel Inhibitor of Angiogenesis

Figure 5

Corneal histology. On day 15, all eyes were enucleated and fixed in formalin. After fixation in formalin, corneas were removed, embedded in paraffin, and stained with hematoxylin and eosin (H&E). Pictured are H&E stained slices taken at the cornea-sclera border. The cornea epithelial surface is facing up. (a) Normal saline (group); (b) bevacizumab 25 mg/mL; (c) Fc-endostatin 2 mg/mL; and (d) Fc-endostatin 20 mg/mL.

(a)

(b)

(c)

(d)