Journal of Ophthalmology / 2015 / Article / Tab 2 / Research Article
Multivariate Analysis of the Ocular Response Analyzer’s Corneal Deformation Response Curve for Early Keratoconus Detection Table 2 Biomechanical descriptors in control and keratoconic eyes. Corneal waveform descriptors of control (group 1) and subclinical keratoconus (group 2) eyes. Data is expressed as mean ± standard deviation. AROC = area under the curve; CI = confidence interval.
Descriptor Group 1 (mean ± SD) Group 2 (mean ± SD) AROC (95% CI) CH 9.62 ± 1.46 8.50 ± 1.36 <0.001 0.71 (0.63–0.79) CRF 9.35 ± 1.46 7.37 ± 1.37 <0.001 0.84 (0.78–0.9) ccCH −0.17 ± 1.30 −1.04 ± 1.19 <0.001 0.70 (0.62–0.78) ccCRF −0.20 ± 1.22 −1.87 ± 1.13 <0.001 0.85 (0.79–0.91) CH-CRF 0.27 ± 0.92 1.13 ± 0.78 <0.001 0.77 (0.84–0.7) timein 7.74 ± 0.39 7.19 ± 0.37 <0.001 0.85 (0.79–0.91) timeout 18.48 ± 0.23 18.35 ± 0.24 0.001 0.65 (0.57–0.74) deltatime 10.74 ± 0.44 11.16 ± 0.45 <0.001 0.76 (0.69–0.84) aindex 7.82 ± 1.14 7.27 ± 1.41 0.008 0.62 (0.53–0.71) bindex 8.16 ± 1.46 6.98 ± 1.87 <0.001 0.68 (0.6–0.77) p1area 3887.14 ± 867.29 3360.05 ± 1279.24 0.003 0.68 (0.59–0.76) p2area 2237.06 ± 626.53 1787.33 ± 609.35 <0.001 0.7 (0.62–0.78) aspect1 20.91 ± 4.59 18.39 ± 5.35 0.002 0.64 (0.56–0.73) aspect2 18.57 ± 7.34 13.73 ± 7.29 <0.001 0.69 (0.61–0.78) uslope1 79.80 ± 22.53 69.10 ± 22.13 0.003 0.64 (0.55–0.73) uslope2 87.20 ± 32.35 66.82 ± 34.67 <0.001 0.69 (0.6–0.77) dslope1 29.72 ± 6.93 26.63 ± 8.57 0.014 0.62 (0.53–0.71) dslope2 24.38 ± 10.35 17.94 ± 9.71 <0.001 0.68 (0.6–0.77) w1 22.30 ± 2.39 22.57 ± 2.84 0.513 0.54 (0.45–0.63) w2 20.35 ± 4.81 22.51 ± 5.87 0.013 0.61 (0.52–0.70) h1 440.97 ± 84.47 386.16 ± 107.79 0.001 0.66 (0.57–0.75) h2 310.47 ± 83.16 235.14 ± 87.32 <0.001 0.74 (0.66–0.82) dive1 367.21 ± 96.01 318.10 ± 99.11 0.002 0.65 (0.56–0.74) dive2 234.06 ± 70.57 173.78 ± 71.64 <0.001 0.74 (0.66–0.81) path1 24.64 ± 3.66 26.02 ± 4.50 0.038 0.6 (0.69–0.51) path2 27.18 ± 4.86 27.44 ± 4.61 0.733 0.52 (0.43–0.61) mslew1 141.48 ± 31.79 128.10 ± 32.48 0.010 0.61 (0.53–0.7) mslew2 138.38 ± 43.12 106.51 ± 41.92 <0.001 0.7 (0.62–0.78) slew1 85.83 ± 23.30 77.59 ± 22.41 0.024 0.62 (0.53–0.71) slew2 89.07 ± 31.61 70.48 ± 33.82 <0.001 0.68 (0.59–0.76) aplhf 1.63 ± 0.33 1.73 ± 0.38 0.105 0.57 (0.65–0.48) p1area1 1612.69 ± 416.66 1381.53 ± 625.19 0.008 0.67 (0.59–0.76) p2area1 937.39 ± 278.33 736.97 ± 290.89 <0.001 0.71 (0.62–0.79) aspect11 30.77 ± 8.38 28.03 ± 9.16 0.052 0.6 (0.51–0.69) aspect21 27.31 ± 10.44 20.31 ± 10.37 <0.001 0.7 (0.62–0.78) uslope11 78.81 ± 22.38 69.05 ± 21.91 0.006 0.64 (0.55–0.72) uslope21 71.29 ± 26.17 55.64 ± 28.37 <0.001 0.68 (0.6–0.76) dslope11 51.57 ± 16.01 48.63 ± 17.63 0.276 0.55 (0.46–0.64) dslope21 42.30 ± 17.25 30.58 ± 16.47 <0.001 0.70 (0.62–0.78) w11 10.98 ± 2.06 10.71 ± 1.90 0.400 0.53 (0.44–0.62) w21 9.31 ± 2.33 10.26 ± 2.88 0.024 0.6 (0.51–0.69) h11 293.98 ± 56.31 257.44 ± 71.86 0.001 0.66 (0.57–0.75) h21 206.98 ± 55.44 156.76 ± 58.22 <0.001 0.74 (0.66–0.82) path11 35.76 ± 5.52 37.56 ± 7.06 0.078 0.59 (0.68–0.5) path21 37.49 ± 6.59 37.87 ± 6.75 0.715 0.51 (0.6–0.42)