Safety and Visual Outcome of Visian Toric ICL Implantation after Corneal Collagen Cross-Linking in Keratoconus: Up to 2 Years of Follow-Up

Table 1

Refractive data at baseline, 6 months after CXL, and 1 and 6 months after Visian toric ICL implantation for keratoconus ( eyes).

Parameter (mean ± SD)	Preoperatively	6 M after CXL; ^a value^*	6 M after ICL; ^b value^*	12 M after ICL; ^c value^*
UDVA ()	1.57 ± 0.50	1.57 ± 0.56; 1.000	0.17 ± 0.06; <0.001	0.17 ± 0.06; 1.000
CDVA ()	0.17 ± 0.08	0.15 ± 0.06; 0.231	0.11 ± 0.05; <0.001	0.11 ± 0.05; 1.000
Sphere (D)	−8.37 ± 3.89	−8.18 ± 3.64; 0.611	−1.38 ± 0.96; <0.001	−1.36 ± 0.94; 1.000
Cylinder (D)	2.95 ± 1.40	2.74 ± 1.33; 0.012	1.12 ± 0.68; <0.001	1.03 ± 0.60; 0.094
SE (D)	−6.96 ± 3.68	−6.81 ± 3.48; 1.000	−0.86 ± 0.86; <0.001	−0.83 ± 0.76; 1.000
(flat) (D)	46.52 ± 3.72	46.23 ± 3.21; 0.588	45.95 ± 3.79; 0.007	45.94 ± 3.79; 1.000
(steep) (D)	50.49 ± 4.42	49.55 ± 4.18; <0.001	49.03 ± 4.61; <0.001	48.98 ± 4.65; 0.587
(max) (D)	53.08 ± 5.17	52.01 ± 4.87; <0.001	51.55 ± 4.78; <0.001	51.55 ± 4.75; 1.000

CXL: corneal collagen cross-linking; ICL: implantable collamer lens; SD: standard deviation; UDVA: uncorrected distance visual acuity; CDVA: corrected distance visual acuity; D: diopters; : keratometry values.
^* value derived from post hoc analysis.
^aComparing 6 months after CXL to preoperative value.
^bComparing 6 months after ICL to preoperative value.
^cComparing 12 months after ICL to 6 months after ICL value.