Safety and Visual Outcome of Visian Toric ICL Implantation after Corneal Collagen Cross-Linking in Keratoconus: Up to 2 Years of Follow-Up

Table 2

Complete case analysis of 10 eyes with 24 months of follow-up ( eyes).

Parameter (mean ± SD)	Preoperatively	6 M after CXL	6 M after ICL	12 M after ICL; ^a value′	24 M after ICL; ^b value′
UDVA ()	1.75 ± 0.56	1.84 ± 0.69	0.17 ± 0.07	0.17 ± 0.06; 0.317	0.17 ± 0.07; 0.317
CDVA ()	0.17 ± 0.07	0.15 ± 0.05	0.12 ± 0.05	0.12 ± 0.05; 1.000	0.12 ± 0.05; 1.000
Sphere (D)	−9.60 ±4.69	−9.55 ± 4.67	−1.83 ± 0.93	−1.75 ± 0.98; 0.317	−1.63 ± 0.95; 0.005
Cylinder (D)	2.55 ± 1.35	2.38 ± 1.29	1.15 ± 0.64	1.00 ± 0.59; 0.034	1.05 ± 0.55; 0.102
SE (D)	−8.32 ± 4.33	−8.36 ± 4.31	−1.34 ± 0.86	−1.17 ± 0.78; 0.027	−1.09 ± 0.75; 0.012
(flat) (D)	45.57 ± 4.13	45.59 ± 3.38	44.97 ± 3.74	44.99 ± 3.76; 0.610	44.93 ± 3.77; 0.131
(steep) (D)	49.17 ± 4.37	48.07 ± 4.42	47.31 ± 4.29	47.25 ± 4.35; 0.256	47.29 ± 4.37; 0.581
(max) (D)	51.16 ± 4.57	50.30 ± 4.55	49.82 ± 4.36	49.80 ± 4.34; 0.715	49.75 ± 4.35; 0.019

CXL: corneal collagen cross-linking; ICL: implantable collamer lens; SD: standard deviation; UDVA: uncorrected distance visual acuity; CDVA: corrected distance visual acuity; D: diopters; : keratometry values.
′ value derived from Wilcoxon Signed Rank test.
^aComparing 12 months after ICL to 6 months after ICL.
^bComparing 24 months after ICL to 6 months after ICL.