Novel GUCY2D Gene Mutations in Japanese Male Twins with Leber Congenital Amaurosis

Table 2

Quality of the targeted-next generation sequencing in this study.

Sample	Number of target regions	Total length of target regions (bp)	Total mapped reads	Mapped reads in targeted region	Specificity (%)	Average coverage	Target covered with at least 1x (%)	Target covered with at least 20x (%)	Target covered with at least 40x (%)
Twin 1 (II-1)	1182	445,968	2,136,143	1,850,847	89.93	263.6	98.56	95.51	91.68
Twin 2 (II-2)	1182	445,968	2,240,650	1,926,085	89.36	274.5	98.58	95.53	91.47