Critical Appraisal of Clinical Practice Guidelines for Age-Related Macular Degeneration

Table 1

Comparison of AGREE II instrument evaluation scores for age-related macular degeneration practice guidelines from the American Academy of Ophthalmology and the Royal College of Ophthalmologists.

AGREE II domain	AAO ratings					RCO ratings
	A	B	C	D	Scaled score	A	B	C	D	Scaled score
(1) Scope and Purpose	6.0	7.0	5.3	5.7	83%	5.0	5.3	6.7	4.0	71%
(2) Stakeholder Involvement	3.7	3.7	3.0	2.0	35%	5.7	6.0	6.7	5.7	83%
(3) Rigor of Development	4.6	4.1	4.9	4.1	57%	2.9	2.6	4.4	3.0	37%
(4) Clarity of Presentation	5.7	5.7	5.7	6.0	79%	5.3	4.0	6.7	5.7	74%
(5) Applicability	5.0	3.5	3.5	2.75	45%	4.5	3.2	5.0	3.0	49%
(6) Editorial Independence	5.0	5.0	4.5	6.0	69%	1.5	1.5	2.5	2.5	17%
Overall Assessment	5	5	5	3	4.5	4	3	6	3	4

Scores were averaged across all items within each domain (maximum item score = 7).
AGREE II = Appraisal of Guidelines for Research and Evaluation II; AAO = American Academy of Ophthalmology; RCO = Royal College of Ophthalmologists.