Research Article

Critical Appraisal of Clinical Practice Guidelines for Age-Related Macular Degeneration

Table 3

Recommendations for improvement from an AGREE II assessment of age-related macular degeneration clinical practice guidelines from the American Academy of Ophthalmology and the Royal College of Ophthalmologists.

Primary recommendationsModel from evaluated CPGs

Stakeholder involvement: clarify roles and input of patient representatives in guideline development and reviewNone
Transparency of guideline development process: clearly delineate roles of each member, evidence search process, methods of guideline development, and reviewNone
Applicability: address facilitators and barriers to application of recommendations by detailing economic factors affecting guideline implementationNone
Editorial independence: disclose methods by which commercial interests were sought and how competing interests may have influenced the recommendation formulation processNone

Additional recommendations

Strengthen stakeholder involvement by including a patient representative and disclosing members’ institutional affiliationsRCO
Improve transparency of development by including evidence ratings and direct evidence citations for each recommendationAAO
Provide summary tables, patient education materials, and list of major recommendations to facilitate their implementationAAO
Ensure and disclose independence of the guideline development group from potential influences of the funding bodyAAO

AGREE II = Appraisal of Guidelines for Research and Evaluation II; AAO = American Academy of Ophthalmology; RCO = Royal College of Ophthalmologists.