The Correlation Analysis between Corneal Biomechanical Properties and the Surgically Induced Corneal High-Order Aberrations after Small Incision Lenticule Extraction and Femtosecond Laser In Situ Keratomileusis

Table 4

Stepwise multivariate linear regression analyses of factors that correlated with the alterations of the total corneal aberrations after SMILE and FS-LASIK.

Changes of total corneal HOAs	SMILE			Adjusted	FS-LASIK			Adjusted
	Priority	Beta			Priority	Beta
3rd- to 6th-order HOAs	MRSE	−0.496	<0.001	0.298	MRSE	−0.760	<0.001
	CRF	−0.281	0.005		CRF	−0.200	0.010
Spherical aberration	MRSE	−0.442	<0.001	0.280	MRSE	−0.697	<0.001
	CRF	−0.335	0.001		CRF	−0.302	<0.001
Vertical coma	MRSE	0.338	0.003	0.136	MRSE	0.304	0.008
	CRF	0.223	0.043
Horizontal coma	MRSE	0.289	0.012	0.084	MRSE	0.594	<0.001

HOAs: high-order aberrations, CRF: corneal resistance factor, MRSE: manifest refraction spherical equivalent, and beta: standardized coefficients.