Joint Effect of CFH and ARMS2/HTRA1 Polymorphisms on Neovascular Age-Related Macular Degeneration in Chinese Population

Table 3

Selected models for nAMD using one to five factors by GMDR.

Number of factors included	Selected factors in the best model	Testing balanced accuracy	Sign test ()	Cross-validation consistency
1	rs3793917	0.6427	0.001	10/10	<0.001
2	rs3793917, rs1061170	0.6450	0.001	10/10	<0.001
3	rs3793917, rs1061170, rs380390	0.6437	0.001	10/10	<0.001
4	rs3793917, rs1061170, rs380390, rs2736912	0.6371	0.001	8/10	<0.001
5	rs3793917, rs1061170, rs380390, rs2736912, smoking status	0.6361	0.001	10/10	<0.001

Empirical value of permutation test.