Expression of HGF and c-Met Proteins in Human Keratoconus Corneas

Figure 3

Representative images of central region of corneas with weak, uniform HGF (green), and c-Met (red) expression in all corneal layers (a). Patchy staining of HGF and c-Met is colocalised in the basal epithelium of both limbal regions (b) and adjacent to cone region of KC (c), with KC showing stronger staining than the limbal region. Strong HGF expression is seen within the stroma of both KC (c and d) and control corneas (a and b). (a) Central region of control cornea, (b) limbal region of control cornea, (c) region adjacent to the cone in KC cornea, (d) cone region in KC cornea, and (e) Ms and Rb Ig control.

(a)

(b)

(c)

(d)

(e)