iTRAQ-Based Proteomic Analysis of Visual Cycle-Associated Proteins in RPE of rd12 Mice before and after RPE65 Gene Delivery

Figure 3

Western blot analysis of differentially expressed proteins. (a) The expression of RALBP-1 and RBP-1 was weak in the untreated rd12 eyes and appeared to increase significantly following gene therapy to levels similar to those present in normal wild-type control eyes. (b) and (c) show the relative grayscale of RALBP-1 and RBP-1 compared to the wild-type values.

(a)

(b)

(c)