Color Doppler Imaging Analysis of Ocular Blood Flow Velocities in Normal Tension Glaucoma Patients: A Meta-Analysis
Table 1
PRISMA 2009 checklist.
Section/topic
#
Checklist item
Reported on page #
Title
Title
1
Identify the report as a systematic review, meta-analysis, or both.
1
Abstract
Structured summary
2
Provide a structured summary including, as applicable, background; objectives; data sources; study eligibility criteria, participants, and interventions; study appraisal and synthesis methods; results; limitations; conclusions and implications of key findings; systematic review registration number.
1
Introduction
Rationale
3
Describe the rationale for the review in the context of what is already known.
1-2
Objectives
4
Provide an explicit statement of questions being addressed with reference to participants, interventions, comparisons, outcomes, and study design (PICOS).
2
Methods
Protocol and registration
5
Indicate if a review protocol exists and if and where it can be accessed (e.g., Web address), and, if available, provide registration information including registration number.
NA
Eligibility criteria
6
Specify study characteristics (e.g., PICOS, length of follow-up) and report characteristics (e.g., years considered, language, and publication status) used as criteria for eligibility, giving rationale.
2-3
Information sources
7
Describe all information sources (e.g., databases with dates of coverage and contact with study authors to identify additional studies) in the search and date last searched.
2
Search
8
Present full electronic search strategy for at least one database, including any limits used, such that it could be repeated.
2
Study selection
9
State the process for selecting studies (i.e., screening and eligibility included in systematic review and, if applicable, included in the meta-analysis).
2-3
Data collection process
10
Describe method of data extraction from reports (e.g., piloted forms, independently, in duplicate) and any processes for obtaining and confirming data from investigators.
3
Data items
11
List and define all variables for which data were sought (e.g., PICOS and funding sources) and any assumptions and simplifications made.
3
Risk of bias in individual studies
12
Describe methods used for assessing risk of bias of individual studies (including specification of whether this was done at the study or outcome level) and how this information is to be used in any data synthesis.
3
Summary measures
13
State the principal summary measures (e.g., risk ratio and difference in means).
3
Synthesis of results
14
Describe the methods of handling data and combining results of studies, if done, including measures of consistency (e.g., ) for each meta-analysis.
3
Risk of bias across studies
15
Specify any assessment of risk of bias that may affect the cumulative evidence (e.g., publication bias, selective reporting within studies).
3
Additional analyses
16
Describe methods of additional analyses (e.g., sensitivity or subgroup analyses and metaregression), if done, indicating which were prespecified.
5
Results
Study selection
17
Give numbers of studies screened, assessed for eligibility, and included in the review, with reasons for exclusions at each stage, ideally with a flow diagram.
5
Study characteristics
18
For each study, present characteristics for which data were extracted (e.g., study size, PICOS, and follow-up period) and provide the citations.
5
Risk of bias within studies
19
Present data on risk of bias of each study and, if available, any outcome level assessment (see Item 12).
6
Results of individual studies
20
For all outcomes considered (benefits or harms), present, for each study, (a) simple summary data for each intervention group and (b) effect estimates and confidence intervals, ideally with a forest plot.
6
Synthesis of results
21
Present results of each meta-analysis done, including confidence intervals and measures of consistency.
6, 10, 13
Risk of bias across studies
22
Present results of any assessment of risk of bias across studies (see Item 15).
5
Additional analysis
23
Give results of additional analyses, if done (e.g., sensitivity or subgroup analyses and metaregression [see Item 16]).
6, 10, 13
Discussion
Summary of evidence
24
Summarize the main findings including the strength of evidence for each main outcome; consider their relevance to key groups (e.g., healthcare providers, users, and policy makers).
13-14, 16, 18
Limitations
25
Discuss limitations at study and outcome level (e.g., risk of bias) and at review level (e.g., incomplete retrieval of identified research and reporting bias).
18, 20
Conclusions
26
Provide a general interpretation of the results in the context of other evidence and implications for future research.
21
Funding
Funding
27
Describe sources of funding for the systematic review and other support (e.g., supply of data); role of funders for the systematic review.
