High MMP-9 Expression May Contribute to Retroprosthetic Membrane Formation after KPro Implantation in Rabbit Corneal Alkali Burn Model

Figure 3

Histopathology of retroprosthetic membrane extracted from the explanted keratoprosthesis in the corneal alkali-burned rabbits. H&E staining of normal cornea ((a) ×100) and retroprosthetic membrane ((b) ×100); transmission electron microscopy of normal cornea ((c) ×4000) and fibrous retroprosthetic membrane ((d) ×4000); immunohistochemical analysis of MMP-9 ((e) ×200) and TIMP-1 ((f) ×200) expressions in normal cornea (MMP-9: (e) ×200; TIMP-1: (g) ×200) and retroprosthetic membrane (MMP-9: (f) ×200; TIMP-1: (h) ×200).

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