Identification of the First De Novo UBIAD1 Gene Mutation Associated with Schnyder Corneal Dystrophy

Figure 2

Slit lamp photomicrographs of 47-year-old woman with Schnyder corneal dystrophy. (A) Diffuse illumination of the right eye demonstrates arcus lipoides and a central crystalline deposit. (B) Diffuse illumination of the left eye also demonstrates dense arcus lipoides, central discoid haze, and a focal central crystalline deposit overlying the inferior pupillary border. (C) Slit illumination of the right eye demonstrates the subepithelial location of the crystalline deposit. (D) Slit lamp photomicrographs of the proband’s father demonstrate arcus senilis but no central stromal opacification in either the right or left eye (top images). The proband’s mother’s corneas are clear (bottom images).