SENP1-Mediated Desumoylation of DBC1 Inhibits Apoptosis Induced by High Glucose in Bovine Retinal Pericytes

Figure 2

High glucose inhibited SENP1 expression in BRPCs and retinas. (a) Western blot analyses of SENP1 protein expression in BRPCs cultured in normal glucose (NG) and high glucose (HG) (12 h, 24 h, and 48 h). (b) Western blot analyses of SENP1 protein expression in the retinas of normal (Norm) and diabetic (Diab) rats. (c) Analyses of SENP1 mRNA in BRPCs cultured in normal glucose (NG) and high glucose (HG) (12 h, 24 h, and 48 h). (d) Analyses of SENP1 mRNA in the retinas of normal (Norm) and diabetic (Diab) rats. Data are presented as their means ± SEM. Bars indicate SDs. versus NG or Norm; versus NG or Norm.

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