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The Role of Inflammation in Age-Related Macular Degeneration

Call for Papers

Increasing evidence suggests that immune-mediated mechanisms are involved in the pathogenesis of age-related macular degeneration (AMD). While AMD is traditionally thought of as a disease confined to the eye, research has suggested that both local and systemic immunological mechanisms may be involved. Inflammation, however, is a double-edged sword; some studies support the notion that inflammation is a risk factor for AMD progression while others state that inflammation is actually protective. Recent theories suggest that inflammation has a dual role with both beneficial and detrimental functions.

We invite investigators to contribute original research articles as well as review articles that will contribute to a greater understanding of the role of inflammation in AMD. As this is an emerging concept, we welcome both clinical and basic science manuscripts. Potential topics include, but are not limited to:

  • Role of the immune system (both local and systemic) in the pathogenesis of AMD
  • Recent anti-inflammatory treatment trials (both local and systemic) for AMD
  • Genetic studies implicating inflammatory mechanisms in AMD
  • Role of the complement system (both local and systemic) in the pathogenesis of AMD
  • Epidemiological studies examining the role of inflammation in AMD
  • Relationship of oxidative stress, angiogenesis, and other mechanisms related to inflammation in AMD

Before submission authors should carefully read over the journal’s Author Guidelines, which are located at http://www.hindawi.com/journals/jop/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/submit/journals/jop/mac/ according to the following timetable:

Manuscript DueFriday, 06 December 2013
First Round of ReviewsFriday, 28 February 2014
Publication DateFriday, 25 April 2014

Lead Guest Editor

  • Catherine Meyerle, Department of Epidemiology and Clinical Applications, National Eye Institute at the National Institutes of Health, Bethesda, MD 20892, USA

Guest Editors

  • Farzin Forooghian, Department of Ophthalmology 8 Visual Sciences, University of British Columbia, Vancouver, BC, Canada V5Z 3N9
  • Steven Yeh, Department of Ophthalmology, Emory Eye Center, Emory University School of Medicine, Atlanta, GA 30322, USA