Review Article

Progesterone and Bone: Actions Promoting Bone Health in Women

Figure 5

The 2-year-change of trabecular lumbar spine bone mineral density documented by Quantitative Computed Tomography (QCT) is shown by rate of ovulatory cycles in 28 women with complete ovulation data out of the 44 women studied prospectively in the ongoing PEKNO-Trial. Assessed by a commercially available ovulation monitor device, ovulation-likelihood was verified by luteal phase serum sampling. The graph illustrates the significant linear relationship (r=0.7; P<.05) observed between the percentage of ovulatory cycles and BMD loss in pre- and perimenopausal women. This figure is from a presentation on the interim analysis by T. Wimmer and V. Seifert-Klauss to the Congress of the German Menopause Society (Deutsche Menopausen Gesellschaft) in Hamburg, November 6th 2009 (unpublished). The authors provide permission.
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