Journal of Osteoporosis

Research Article

Testosterone and the Male Skeleton: A Dual Mode of Action

Table 3

Relative effects of testosterone, dihydrotestosterone, estradiol, and selective estrogen receptor modulator on body weight, appendicular skeletal growth, cancellous bone mass, and on cortical bone area.
Body weight gainAppendicular skeletal growthCancellous bone massCortical bone area
Orch + T=, =,
Orch + DHT=, =, =,
Orch + E2=, = =,
Orch + SERM NA
Orch: orchidectomy; T: testosterone; DHT: dihydrotestosterone; E2: estradiol; SERM: selective estrogen receptor modulator.