Detecting Early Biomechanical Effects of Zoledronic Acid on Femurs of Osteoporotic Female Rats

Table 2

Yield point (N) at 9 and 12 months.

Group	Yield Point
	9 months			12 months
	Animal	Measurement (N)	Mean ± SD	Animal	Measurement (N)	Mean ± SD
ODW	1	122.8	113.0 ± 11.4	11	113.3	105.7 ± 9.0
	2	110.5		12	90.8
	3	120.3		13	102.4
	4	97.5		14	106.3
	5	117.1		15	107.6
	6	97.7		16	118.1
	7	118.5		17	115.2
	8	123.5		18	98.6
	9	97.5		19	95.4
	10	125.0		20	110.6
OZA	31	127.4	129.7 ± 6.0	21	100.5	119.8 ± 9.7
	32	131.8		22	111.4
	33	134.2		23	124.5
	34	123.5		24	130.6
	35	125.1		25	119.2
	36	122.5		26	119.5
	37	131.8		27	134.0
	38	127.5		28	122.2
	39	130.4		29	112.6
	40	143.2		30	123.7
SDW	41	113.5	125.3 ± 9.1	51	124.0	112.6 ± 6.2
	42	119.4		52	103.7
	43	118.2		53	114.1
	44	119.6		54	107.3
	45	131.1		55	106.5
	46	133.2		56	111.6
	47	135.7		57	116.2
	48	129.8		58	115.2
	49	137.9		59	108.3
	50	114.6		60	118.1
SZA	71	133.3	137.0 ± 10.7	61	103.9	124.6 ± 16.8
	72	124.4		62	128.5
	73	141.0		63	111.4
	74	135.8		64	126.7
	75	149.5		65	120.0
	76	152.0		66	152.1
	77	139.8		67	110.4
	78	116.1		68	128.7
	79	137.2		69	112.2
	80	141.7		70	152.3