Effects of Vitamin E on Bone Biomechanical and Histomorphometric Parameters in Ovariectomized Rats

Table 2

Effects of ovariectomy (Ovx) and three doses of vitamin E: low dose (LD, 300 mg/kg diet), medium dose (MD, 525 mg/kg diet), and high dose (HD, 750 mg/kg diet) on DXA bone parameters of whole body and fourth lumbar vertebrae (L4).

Parameters	Sham	Ovx	LD	MD	HD
Whole body (g)
Baseline
BMC (g)	10.3±0.38	10.55±0.20	10.84±0.18	10.57±0.22	10.73±0.21
BMD (g/cm^2)	0.1774±0.0029	0.1811±0.0030	0.1806±0.0013	0.1790±0.0020	0.1799±0.0018
Final
BMC (g)	11.14±0.40	11.72±0.22	11.98±0.16	11.59±0.26	11.8±0.20
BMD (g/cm^2)	0.1734±0.0029^a	0.1657±0.0021^a	0.1635±0.0013^ab	0.1649±0.0020^a	0.1644±0.0018^ab
L4 vertebra
BMD (g/cm^2)	0.240±0.005^a	0.199±0.004^b	0.202±0.004^b	0.199±0.004^b	0.199±0.004^b

Values within a row that share the same superscript letters are not significantly (𝑃≥.05) different. Values are means ± S.E.M.
BMC: bone mineral content; BMD: bone mineral density.