Research Article

The Combination Therapy with Zoledronic Acid and Propranolol Improves the Trabecular Microarchitecture and Mechanical Property in an Rat Model of Postmenopausal Osteoporosis

Table 1

Effects of zoledronic acid, propranolol, or zoledronic acid plus propranolol on body weight.

GroupBody weight (g)

SHAM304.0 ± 10.65***
OVX396.6 ± 8.92
ZOL 100355.0 ± 8.51
ZOL 50352.0 ± 9.82
PRO367.0 ± 8.45
ZOL 50 + PRO359.6 ± 13.14

Data are shown as the mean ± SD ( ), evaluated by Tukey’s multiple comparison test. , compared to OVX group. All groups except SHAM group undergo ovariectomy.