Association of Bone Loss with the Upregulation of Survival-Related Genes and Concomitant Downregulation of Mammalian Target of Rapamycin and Osteoblast Differentiation-Related Genes in the Peripheral Blood of Late Postmenopausal Osteoporotic Women

<div>Relative expression<i> of RUNX2, ALPL, TGF<i>β</i>1, cathepsin K, MMP-9, TNF<i>α</i>, IL-1<i>β</i>, mTOR, ULK1, caspase-3, </i>and<i> p21</i> genes with reference to <i>β-actin</i> gene in the peripheral blood of 22 postmenopausal OP patients compared to 26 healthy age-matched control women (control). Each point represents the mean ± SD. Significant differences as compared to the control are indicated by asterisks.</div>

Journal of Osteoporosis

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Figure 1

Figure 1: Association of Bone Loss with the Upregulation of Survival-Related Genes and Concomitant Downregulation of Mammalian Target of Rapamycin and Osteoblast Differentiation-Related Genes in the Peripheral Blood of Late Postmenopausal Osteoporotic Women 

Figure 1 | Association of Bone Loss with the Upregulation of Survival-Related Genes and Concomitant Downregulation of Mammalian Target of Rapamycin and Osteoblast Differentiation-Related Genes in the Peripheral Blood of Late Postmenopausal Osteoporotic Women 