Strategies for Diagnosis and Prevention of Venous Thromboembolism during Pregnancy

Table 6

Thromboprophylaxis using UFH—dosage and monitoring.

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(1) Low-dose prophylaxis

 (a) First trimester: 5000 to 7000 Units q12 hours

 (b) Second trimester: 7500 to 10,000 Units q12 hours

 (c) Third trimester: 10,000 Units q12 hours

  (i) Unless aPTT elevated

(2) Adjusted dose prophylaxis to aPTT of 1.5 to 2.5

 (a) Dose: 10,000 q8–12 hours

 (b) Goal aPTT: 1.5 to 2.5 times normal

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