Research Article
An Obesity-Related FTO Variant and the Risk of Preeclampsia in a Finnish Study Population
Table 1
Background characteristics of the Finnish preeclampsia patients and control subjects from data sets 1, 2, and 3.
| | | Preeclampsia | Controls | | | | Primiparous (n = 321) | Multiparous (n = 164) | Primiparous (n = 264) | Multiparous (n = 185) | Primiparous | Multiparous | | | N | Mean | SD | N | Mean | SD | N | Mean | SD | N | Mean | SD | P
*
| P
*
|
| | Age (years) | 321 | 28.0 | 5.4 | 164 | 31.8 | 5.2 | 264 | 27.6 | 4.7 | 185 | 31.0 | 4.9 | 0.381 | 0.177 | | BMI (kg/m2) | 309 | 23.7 | 4.4 | 163 | 24.4 | 4.4 | 261 | 22.4 | 3.3 | 183 | 23.4 | 3.7 | <0.001 | 0.055 | | Systolic BP (mmHg) | 315 | 167.0 | 18.4 | 154 | 169.6 | 17.1 | 80 | 118.6 | 9.0 | 22 | 119.1 | 11.9 | <0.001 | <0.001 | | Diastolic BP (mmHg) | 316 | 105.7 | 10.1 | 154 | 105.1 | 10.4 | 80 | 73.6 | 7.8 | 22 | 72.2 | 8.9 | <0.001 | <0.001 | | Birth weight (g) | 320 | 2400 | 934.6 | 162 | 2382.6 | 863.2 | 264 | 3537.8 | 404.0 | 185 | 3635.0 | 412.8 | <0.001 | <0.001 | | Relative birth weight (SD) | 311 | −1.3 | 1.3 | 160 | −1.2 | 1.3 | 262 | −0.2 | 0.8 | 183 | 0.0 | 0.8 | <0.001 | <0.001 | | Gestational age at birth (weeks) | 315 | 35.7 | 3.9 | 164 | 35.5 | 3.5 | 264 | 39.9 | 1.5 | 185 | 40.0 | 1.2 | <0.001 | <0.001 |
| | | N | % | | N | % | | N | % | | N | % | | P
**
| P
**
|
| | Gestational diabetes | 16 | 5.0 | | 7 | 4.3 | | 5 | 1.9 | | 12 | 6.5 | | 0.046 | 0.362 | | Pregestational diabetes | 8 | 2.5 | | 5 | 3.0 | | 1 | 0.4 | | 1 | 0.5 | | 0.046 | 0.103 |
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*Student’s t-test or Mann-Whitney test. **Chi-square test or Fisher’s exact test.
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