Effect of Angiotensin II on the Left Ventricular Function in a Near-Term Fetal Sheep with Metabolic Acidemia

Table 4

Fetal left ventricular tissue Doppler-derived parameters at baseline and during angiotensin II infusion. Data are presented as mean (SD) or n (%).

	Baseline	Angiotensin II	𝑃 value
IVCV, cm/s	4.1 (2.3)	6.4 (2.4)	0.039
IVCVAccel, cm/s^2	350 (250)	780 (490)	0.022
S′-velocity, cm/s	4.7 (1.5)	5.7 (2.4)	0.165
IVRV, cm/s	2.2 (1.4)	0.6 (1.5)	0.15
Absent IVRV, n (%)	2 (20)	8 (80)	0.024
E′-velocity, cm/s	3.1 (0.74)	4.4 (0.83)	0.015
A′-velocity, cm/s	8.2 (4.0)	12.9 (6.5)	0.073
E/E′ ratio	8.7 (2.0)	5.7 (2.1)	0.015
IVCT%	10.4 (4.2)	12.6 (4.8)	0.166
IVRT%	13.3 (7.8)	12.3 (6.1)	0.745

IVCV, isovolumic contraction velocity; IVCVAccel, isovolumic myocardial acceleration; S′-velocity, myocardial velocity during the left ventricular systole; IVRV, isovolumic relaxation velocity; E′-velocity, myocardial velocity during early ventricular filling; A′-velocity, myocardial velocity during atrial contraction; IVCT, isovolumic contraction time; IVRT, isovolumic relaxation time.