Use of Medicines with Unknown Fetal Risk among Parturient Women from the 2004 Pelotas Birth Cohort (Brazil)
Table 3
Description of the sample and the health conditions of the mothers participating in the 2004 Birth Cohort (), prevalence (%) and adjusted analyses of the use of medicines during pregnancy considering all medicines and the medicines with unknown fetal risk used. Birth Cohort of Pelotas, RS 2004.
Use of medicines (total)
Use of medicines with unknown fetal risk
Characteristic
Adjusted analyses
Adjusted analyses
%
PR (IC 95%)
value
%
PR (IC 95%)
value
Total of participants
4,189
92.7
—
—
52.5
—
—
Age
0,062
0.076
<20
796
90.8
1.00
43.6
1.00
20 to 29
2,085
93.1
1.58 (1.03–2.43)
53.2
1.09 (0.90–1.32)
30 to 39
1,170
92.9
2.01 (1.19–3.38)
56.9
1.31 (1.05–1.64)
40 or more
136
94.1
2.35 (0.83–6.62)
55.1
1.18 (0.76–1.84)
Skin color
0,08
<0.001
White
2,555
93.8
1.31 (0.97–1.78)
57.7
1.36 (1.17–1.58)
Non-white
1,586
90.9
1.00
44.1
1.00
Education in years
0.026
<0.001
0 to 4
647
87.3
1.00
32.8
1.00
5 to 8
1,711
91.6
1.50 (1.02–2.23)
47.0
1.70 (1.35–2.13)
9 to 11
1,396
95.1
1.90 (1.19–3.03)
62.7
2.57 (2.01–3.30)
12 or more
435
97.2
2.66 (1.22–5.79)
70.6
2.74 (1.95–3.85)
Marital status
0.064
0.92
With the baby’s father
3,502
93.1
1.44 (0.98–2.11)
53.5
0.99 (0.81–1.21)
Without
687
90.5
1.00
47.0
1.00
Income per capita
0.09
<0.001
1st quintile
830
88.4
1.00
38.2
1.00
2nd quintile
834
89.2
0.83 (0.55–1.25)
41.7
1.03 (0.82–1,30)
3rd quintile
886
94.2
1,48 (0.93–2.36)
52.7
1.29 (1.03–1.62)
4th quintile
849
94.7
1.11 (0.68–1.82)
61.1
1.79 (1.41–2.27)
5th quintile
790
96.8
1.55 (0.81–2.95)
69.2
1.94 (1.47–2.55)
Parity
0.025
0.52
primipara
1,658
94.8
2.45 (1.34–4.46)
55.9
1.12 (0.81–1.56)
1 or 2
1,086
93.0
1.65 (0.96–2.82)
54.8
1.06 (0.78–1.45)
3 or 4
1,026
91.6
1.36 (0.83–2.23)
48.6
0.95 (0.70–1.27)
5 or more
419
86.2
1.00
42.2
1.00
Prenatal consultation
0.004
0.001
<6
689
86.6
1.00
36.0
1.00
6 or more
3,250
94.9
1.65 (1.18–2.32)
56.8
1.39 (1.14–1.70)
Start of prenatal care
0.70
0.32
Before the 20th week
3,765
94.0
1.10 (0.68–1.80)
54.8
1.18 (0.85–1.64)
After the 20th week
283
84.8
1.00
31.4
1.00
Hospitalization
No
3,722
91.9
1.00
0.002
50.9
1.00
0.05
Yes
467
98.9
6.50 (1.99–21.21)
64.7
1.28 (1.00–1.62)
High Blood Pressure
0.012
0.87
No
3,189
92.3
1.00
52.6
1.00
Yes
992
94.0
1.60 (1.11–2.31)
52.3
0.90 (0.59–1.37)
Diabetes
0.76
0.63
No
4,062
92.6
1.00
52.4
1.00
Yes
124
96.0
0.86 (0.32–2.30)
56.4
0.90 (0.59–1.37)
Depression
0.034
<0.001
No
3,138
92.1
1.00
51.0
1.00
Yes
1049
94.3
1.49 (1.03–2.16)
56.9
1.38 (1.16–1.64)
Anemia
<0.001
<0.001
No
1,402
83.0
1.00
42.7
1.00
Yes
2756
97.8
10.79 (7.68–15.16)
57.7
1.53 (1.31–1.78)
Threat of abortion
0.15
<0.001
No
3,736
92.2
1.00
50.0
1.00
Yes
449
96.4
1.55 (0.85–2.83)
73.0
2.40 (1.84–3.11)
Threat of premature labor
<0.001
<0.001
Não
3,416
91.7
1.00
48.0
1.00
Sim
771
97.0
2.72 (1.57–4.73)
72.5
2.65 (2.15–3.27)
Urinary Infection
<0.001
0.012
Não
2,623
89,8
1.00
52.5
1.00
Sim
1,552
97.7
5.53 (3.58–8.54)
52.5
0.82 (0.71–0.96)
*Chi square test; **1st quintile relates to the most deprived quintile ***PR: prevalence ratio.
