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| (1) | Any of the cardiac valve diseases with functional class 3-4 heart failure that is not reversible to class 2 |
| (2) | Any kind of acute heart disease except coronary heart disease that has reached functional class 3-4 (e.g., myocarditis and pericarditis) |
| (3) | History of dilated cardiomyopathy in previous pregnancies |
| (4) | Marfan syndrome, when ascending aorta is wider than 5 cm |
| (5) | Eisenmenger's syndrome |
| (6) | Pregnancy-induced fatty liver |
| (7) | Grade 3 esophageal varicosities |
| (8) | History of esophageal varicosities hemorrhage followed by portal hypertension |
| (9) | Uncontrollable autoimmune hepatitis |
| (10) | Renal failure |
| (11) | Hypertension which is not controllable with permitted drugs during pregnancy |
| (12) | Any of the pulmonary diseases that lead to pulmonary hypertension even to a mild degree (emphysema, fibrosis, diffuse bronchiectasis) |
| (13) | Any infection with HIV virus which has entered into the phase of AIDS disease |
| (14) | Hypercoagulability when using heparin leads to progression of other diseases that can threat’s motheren life |
| (15) | Active uncontrollable SLE which has involved a major organ |
| (16) | Vasculitis (when major organs are involved) |
| (17) | All CNS masses with considering their type and location, when beginning the treatment is dangerous to fetus and without treatment mother-life may be threatened |
| (18) | Pemphigus vulgaris and severe generalized psoriasis and advanced melanoma |
| (19) | Multidrug-resistant epilepsies |
| (20) | MS cases in which the patient is disabled |
| (21) | Myasthenia gravis |
| (22) | Some type of motor neuron diseases like ALS which is intensified following pregnancy and will seriously endanger mother’s life |
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