Developmental Programming in Response to Intrauterine Growth Restriction Impairs Myoblast Function and Skeletal Muscle Metabolism

Figure 1

The stages of skeletal muscle formation relative to gestational age are depicted by the horizontal arrows and schematic diagrams (fascicular cross-sections) for the developmental process. The vertical dashed line represents the completion of myogenesis (new fiber formation) and onset of hypertrophic fiber growth. The timing, duration, and type of nutritional insult (red boxes) reported in various studies are presented below the gestational timeline, along with the fetal consequences (blue boxes).