Inflammatory Disturbances in Preeclampsia: Relationship between Maternal and Umbilical Cord Blood

Table 2

Oxidative stress parameters, cytokines, and acute-phase proteins in maternal and cord blood, in normal and PE cases.

	Maternal			UCB
	Normal (𝑛=42)	PE (𝑛=46)	P Value	Normal (𝑛=40)	PE (𝑛=42)	P Value
Uric acid (mg/dL)	4.2±1.3	5.5±1.6	<0.001	4.5±1.1 (𝑛=39)	5.7±1.6 (𝑛=40)	<0.001
TAS (mmol/L)	1.10±0.22	1.07±0.3	0.55	1.23±0.27 (𝑛=39)	1.17±0.26 (𝑛=41)	0.143
TBARS (μmol/L)	1.50 (1.29; 1.81) (𝑛=40)	1.87 (1.49; 2.38) (𝑛=43)	0.013	1.08 (0.95; 1.26) (𝑛=35)	1.10 (0.85; 1.36) (𝑛=35)	0.99
TBARS/TAS	1.48 (1.19; 1.66) (𝑛=40)	1.76 (1.46; 2.13) (𝑛=43)	0.003	0.93 (0.76; 1.31) (𝑛=35)	0.93 (0.71; 1.25) (𝑛=35)	0.84
IL-6 (pg/mL)	1.9 (1.2; 6.4)	4.0 (2.3; 10.1) (𝑛=42)	0.013	1.8 (1.2; 2.8)	2.2 (1.5; 5.6)	0.066
TNF-α (pg/mL)	1.2 (1.0; 1.6)	1.9 (1.3; 2.4) (𝑛=43)	0.001	1.9 (1.4; 2.4)	1.8 (1.5; 2.1)	0.34
α1-Antitrypsin (mg/dL)	191.6±57.0	250.5±74.9	<0.001	120.2±30.1 (𝑛=39)	134.1±23.5 (𝑛=40)	0.025
CRP (mg/L)	3.1 (1.4; 5.8)	4.1 (2.5; 7.9)	0.033	0.03 (0.02; 0.04) (𝑛=39)	0.04 (0.02; 0.08)	0.011

𝑛, number of cases; PE, Preeclampsia; UCB, umbilical cord blood.