Inflammatory Disturbances in Preeclampsia: Relationship between Maternal and Umbilical Cord Blood

Table 3

Leukocyte activation parameters in maternal and umbilical cord blood, in normal and PE cases.

	Maternal			UCB
	Normal (𝑛=42)	PE (𝑛=46)	P Value	Normal (𝑛=39)	PE (𝑛=42)	P Value
Leukocytes (×10^9/L)	10.8±3.9	11.90±3.74	0.19	12.2±3.5 (𝑛=41)	9.6±4.8 (𝑛=46)	0.006
Neutrophils (×10^9/L)	8.4±3.7	9.17±3.74	0.32	5.7±2.1 (𝑛=40)	4.04±2.8 (𝑛=46)	0.002
Eosinophils (× 10^9/L)	0.07±0.09	0.056±0.093	0.38	0.5±0.41 (𝑛=40)	0.32±0.35 (𝑛=46)	0.033
Basophils (×10^9/L)	0.007±0.026	0.025±0.039	0.01	0.06±0.077	0.035±0.064	0.073
Lymphocytes (×10^9/L)	1.9±0.6	2.22±1.06	0.10	5.19±1.37	4.46±1.82	0.044
Monocytes (×10^9/L)	0.4±0.3	0.39±0.21	0.89	0.86±0.51	0.65±0.44	0.039
Metamyelocytes (n)	10	6	0.27	19	17	0.38
Myelocytes (n)	3	1	0.34	10	5	0.15
sVCAM (ng/mL)	816.1±200.9 (𝑛=38)	948.6±360.4 (𝑛=45)	0.04	2581.6±1081.6 (𝑛=34)	3101.4±1090.8 (𝑛=39)	0.045
sPECAM (ng/mL)	146.9±25.5 (𝑛=39)	142.8±28.3 (𝑛=45)	0.49	114.0±17.3 (𝑛=35)	108.7±18.7 (𝑛=37)	0.22
sL-selectin (ng/mL)	640.6±119.6 (𝑛=38)	564.2±119.1 (𝑛=42)	0.005	697.8±127.5 (𝑛=38)	587.0±148.3 (𝑛=42)	0.001
Elastase (ng/mL)	52.0 (39.9; 64.8) (𝑛=38)	60.8 (47.6; 75.9) (𝑛=41)	0.16	41.3 (27.8; 54.7) (𝑛=37)	28.4 (20.7; 41.4) (𝑛=41)	0.013
Elastase/Neutrophil (pg)	6.7 (5.5; 8.3) (𝑛=38)	7.2 (4.7; 9.4) (𝑛=41)	0.9	6.2 (5.1; 9.9) (𝑛=37)	8.5 (5.3; 12.3) (𝑛=41)	0.09
Elastase/α1-Antitrypsin (×10^−4)	0.27 (0.20; 0.43) (𝑛=38)	0.25 (0.18; 0.32) (𝑛=41)	0.22	0.33 (0.23; 0.46) (𝑛=35)	0.22 (0.15; 0.34) (𝑛=37)	0.007
Lactoferrin (ng/mL)	307.0 (254.5; 537.5)	331.0 (240.0; 659.0) (𝑛=43)	0.81	337.5 (256.3; 494.0) (𝑛=40)	234.0 (180.0; 376.0) (𝑛=43)	0.017
Lactoferrin/Neutrophil (pg)	43.7 (30.6; 68.7) (𝑛=42)	35.4 (24.2; 78.7) (𝑛=40)	0.40	70.9 (42.3; 106.2) (𝑛=39)	66.2 (47.5; 111.3) (𝑛=41)	0.39

n, number of cases; PE, Preeclampsia; UCB, umbilical cord blood.