Differential Effects of Chronic Pulsatile versus Chronic Constant Maternal Hyperglycemia on Fetal Pancreatic β-Cells
Figure 1
Maternal and fetal glucose and fetal insulin concentrations. Maternal (a) and fetal (b) arterial plasma glucose and fetal arterial plasma insulin (c) concentrations were measured throughout the infusion in CHG (, ), PHG (, ), and control animals (, ). ** indicates a significant difference between both CHG and PHG from controls for maternal glucose concentrations, . ## indicates a significant difference between CHG and PHG animals for maternal glucose concentrations, <0.0001. * indicates a significant difference between CHG and both PHG and control groups for fetal arterial glucose and insulin concentrations, . # indicates a significant increase in CHG fetuses only compared to their baseline (Day 1) for fetal arterial insulin concentrations, .
