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Journal of Pregnancy
Volume 2013 (2013), Article ID 826045, 6 pages
http://dx.doi.org/10.1155/2013/826045
Clinical Study

Eclampsia Characteristics and Outcomes: A Comparison of Two Eras

1Department of Obstetrics and Gynecology, University of Tennessee Health Science Center, 853 Jefferson Avenue, Room E102, Memphis, TN 38163, USA
2Eastern Virginia Medical School, 825 Faifax Avenue, Norfolk, VA 23507, USA

Received 19 January 2013; Accepted 6 March 2013

Academic Editor: Antonio Farina

Copyright © 2013 Mauro H. Schenone et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Objective. To describe the trends in incidence, characteristics, and outcomes of women with eclampsia. Methods. We reviewed and abstracted data from medical records of all women diagnosed with eclampsia in our institution from August 1998 to April 2011. In addition to overall characteristics and outcomes, the cases were stratified by onset: antenatal versus postnatal and early (<32 weeks of gestation) versus late antenatal cases (≥32 weeks of gestation). Comparisons were made using chi-square, Fisher's exact, Mann-Whitney U, and t-tests. A two-sided was considered statistically significant. Results. We identified 87 eclampsia cases out of 59,388 deliveries; 62 cases were diagnosed before delivery, and 25 had a postnatal onset. Among the 62 antenatal cases, 41 were diagnosed before 32 weeks and 21 at or after 32 weeks of gestation. Antenatal cases had higher systolic ( ) and diastolic ( ) blood pressures, more abnormal dipstick-test proteinuria ( ), and lower platelet counts ( ) than postnatal cases. Early eclampsia cases were complicated more often with HELLP syndrome than late eclampsia cases ( ). Conclusion. The occurrence of eclampsia has decreased over time. The earlier the onset is, the worse the outcome appears to be.