Impaired Fertility Associated with Subclinical Hypothyroidism and Thyroid Autoimmunity: The Danish General Suburban Population Study

Table 3

Table of odds ratios for ≥1 children born, ≥1 pregnancy, and spontaneous abortion in patients with prevalent hypothyroidism versus controls and in patients with mild (subclinical) hypothyroidism versus controls.

	Prevalent hypothyroidism				Mild (subclinical) hypothyroidism
	Odds ratio (95% CI)	value	Odds ratio (95% CI)	-value	Odds ratio (95% CI)	-value	Odds ratio (95% CI)	-value
	Age-adjusted		Multiadjusted		Age-adjusted		Multiadjusted
≥1 children born versus none	0.84 (0.67–1.06)	0.14	0.87 (0.69–1.10)	0.25	0.75 (0.60–0.94)	0.01	0.71 (0.56–0.90)	0.004
≥1 pregnancy versus none	0.83 (0.65–1.07)	0.15	0.85 (0.66–1.1)	0.22	0.79 (0.61–1.01)	0.06	0.75 (0.58–0.97)	0.03
Spontaneous abortion (yes versus no)	1.05 (0.88–1.24)	0.6	1.02 (0.89–1.22)	0.78	0.99 (0.82–1.19)	0.87	0.96 (0.79–1.17)	0.69

Multiadjusted model: age, menopause, BMI, smoking, diabetes, antihypertensive medication, cholesterol lowering medication, contraception, income, unemployment, and education.