Review Article

Lipid Droplets and Mycobacterium leprae Infection

Figure 2

Schematic representation of putative genes involved in TAG biosynthesis in M. leprae. As a precursor, glycerol-3-phosphate further processed by sequential acylation steps, until last the transesterification of diacylglycerol (DAG) to triacylglycerol (TAG). Reaction 1 mediated by glycerol-3-phosphate acyltransferase, 1-acylglycerol-3-phosphate acyltransferase mediates reaction 2, phosphatidc acid phosphatase processes reaction 3, and the last reaction 4 is mediated by acyl-CoA: diacylglycerol acyltransferase enzyme.
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