Research Article

Prevalence of Plasmid-Mediated Quinolone Resistance Genes among Extended-Spectrum β-Lactamase-Producing Klebsiella pneumoniae Human Isolates in Iran

Table 3

Association between patient characteristics and acquisition of extended-spectrum β-lactamase-producing Klebsiella pneumoniae infection.

Patient characteristicESBL-negative 
= 98 (%)
ESBL-positive 
= 87 (%)
value

Age
 >50 years 36 (36.7)56 (64.4)≤0.001
 ≤50 years 62 (63.3)31 (35.6)
Sex
 Male27 (27.6)39 (44.8)0.05
 Female71 (72.4)48 (55.2)
Ward
 ICU15 (33.3)23 (28)≤0.001
 Internal medicine7 (15.6)10 (12.2)
 Infectious5 (11.1)14 (17.1)
 Surgery6 (13.3)12 (14.6)
 Gynecology4 (8.9)7 (8.5)
 Pediatric5 (11.1)7 (8.5)
 Emergency1 (2.2)6 (7.3)
 CCU2 (4.4)3 (3.7)
Sample type 0.001
 Urine74 (75.5)45 (51.7)
 CSF1 (1)1 (1.1)
 Catheters1 (1)2 (2.3)
 Blood5 (5.1)1 (1.1)
 Wound3 (3.1)6 (6.9)
 Respiratory14 (14.3)32 (36.8)
Drug resistance
 Fluoroquinolones resistance5 (5.1)78 (89.7)≤0.001
 Multidrug resistance62 (63.3)87 (100.0)