Evaluating Antiplasmodial and Antimalarial Activities of Soybean (Glycine max) Seed Extracts on P. falciparum Parasite Cultures and P. berghei-Infected Mice
Table 4
In vivo antimalarial activities of crude extract of Glycine max in curative test on day 4 and animal survival time.
Treatment
Dose (mg/kg)
Mean ± SD parasitemia (%)
% suppression of parasite
Mean survival time (days)
Methanol extract
200
5.99 ± 0.18
53.45
10.50 ± 0.58
400
4.54 ± 0.22
64.67
11.25 ± 0.96
800
3.48 ± 0.37
72.93
16.25 ± 0.96
Peptide extract
200
5.87 ± 0.25
54.39
11.00 ± 0.82
400
4.52 ± 0.13
64.89
12.40 ± 1.14
800
3.61 ± 0.27
71.90
15.60 ± 1.52
CQ
1.19 ± 0.36
90.72
28.25 ± 1.50
Vehicle (3% dimethyl sulfoxide and 10% tween 80 in PBS)
