Plantago ovata F. Mucilage-Alginate Mucoadhesive Beads for Controlled Release of Glibenclamide: Development, Optimization, and In Vitro-In Vivo Evaluation

Figure 16

Comparative in vivo mean percentage reduction in blood glucose level in alloxan-induced diabetic rats after oral administration of pure glibenclamide and optimized glibenclamide-loaded IHM-alginate mucoadhesive beads (F-O).