Research Article
Cellular Redox Status Regulates Emodin-Induced Radiosensitization of Nasopharyngeal Carcinoma Cells In Vitro and In Vivo
Table 6
Maximum tumor diameter doubling time and tumor growth delay associated with different treatments (
,
).
| Group | Maximum tumor diameter doubling time/day | Tumor growth delay/day | Enhancement factor/% |
| Control group | 17.02 ± 1.12 | — | | Solvent group | 17.14 ± 0.63 | 0.12 | | Low-dose emodin (4 mg/kg) | 17.20 ± 0.84 | 0.20 | | High-dose emodin (12 mg/kg) | 17.40 ± 1.01 | 0.40 | | radiotherapy group | 21.30 ± 1.14* | 4.28 | | Low-dose emodin + 2 Gy | 24.10 ± 0.72** | 6.90 | 1.612 | High-dose emodin + 2 Gy | 25.17 ± 0.64** | 8.15 | 1.904 |
|
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= 4.318, P < 0.05, Radiotherapy group compared to control group, ** = 2.163, P < 0.05, combined group versus simple radiotherapy group.
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