Research Article
Optimization of Carboxymethyl-Xyloglucan-Based Tramadol Matrix Tablets Using Simplex Centroid Mixture Design
Table 10
Analysis of variance (ANOVA) for all two responses.
| | % Release at 2 hour | | % Release at 8 hour | Source | | | Source | | | | F-value | P value | | F-value | P value |
| Model | 344.65 | 0.0409 | Model | 272.39 | 0.004 | Linear mixture | 389.03 | 0.0358 | Linear mixture | 162.92 | 0.0003 | AB | 490.78 | 0.0287 | AB | 56.11 | 0.0003 | BC | 58.17 | 0.0830 | AC | 23.94 | 0.0005 | ABC | 741.53 | 0.0234 | | 19.97 | 0.0006 |
|
|