Research Article
Quantification of Lumefantrine in Human Plasma Using LC-MS/MS and Its Application to a Bioequivalence Study
Table 1
Intrarun and interrun precision and accuracy (n = 6) of lumefantrine in human plasma.
| Run | Concentration added (ng/mL) | Mean concentration found (ng/mL) | % CV | % RE |
| Intra- | 201.01 | 189.45 | 6.66 |
−5.75
| 600.70 | 560.22 | 4.95 |
−6.74
| 10011.60 | 9566.39 | 4 .88 |
−4.45
| 17019.71 | 15705.69 | 3.69 |
−7.72
| 20023.19 | 18693.52 | 6.11 |
−6.64
|
| Inter- | 201.01 | 188.90 | 5.56 |
−6.02
| 600.70 | 581.70 | 5.99 |
−3.16
| 10011.60 | 9727.42 | 9.14 |
−2.84
| 17019.71 | 16097.79 | 4.87 |
−5.42
| 20023.19 | 18804.76 | 3.80 |
−6.09
|
|
|
CV: coefficient of variation; RE: relative error.
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